Blisters after burns squeeze out water and then have water, is due to burns early shallow second-degree or deep second-degree trauma inflammatory reaction and so on, can be disposed of by regular disinfection and pumping, bandage and dressing, drug treatment and so on. Second-degree burn wound early due to increased skin capillary permeability, causing tissue fluid exudation, so the early days of wound secretion and exudate a lot. The wound can be sterilized by iodine povidone and then bandaged with sterile gauze and treated with regular dressing changes. It can remove the wound secretion and exudate contamination in time, reduce the chance of infection and promote healing. When changing the dressing, the wound can be externally applied epidermal cell growth factor gel and other drugs to promote wound healing, which can reduce the exudate. At the same time need to take amoxicillin, cefaclor and other antibiotics to prevent infection, accelerate the healing speed. If oozing persists after the burn, it is recommended to go to the hospital in time, under the guidance of the doctor to avoid delaying the injury and causing other damage.