Difficulty in urination is not allowed to take Mirabelone. Choose the appropriate medication according to the different causes of urination difficulties. Mirabelone is used to treat patients with urinary frequency, urgency and/or urge incontinence, and is not suitable for use by people with difficulty in urination as it may cause worsening of symptoms. Difficulty in urination may be caused by urinary tract infection, prostate enlargement, urinary stones and other reasons. 1. Urinary tract infection: If patients have difficulty urinating due to urinary tract infection, they can be treated with medications under the guidance of a doctor, such as amoxicillin capsules, cefixime and so on. 2. Prostatic hyperplasia: prostatic hyperplasia in older men can lead to urinary difficulties, and can be treated with medications under the guidance of a doctor, such as tamsulosin hydrochloride extended-release capsules, finasteride and so on. 3. Urinary stones: patients with urinary stones blocking the urethra, can also cause urinary difficulties, this time to drink more water to promote the discharge of stones, if the symptoms have not improved, it is recommended to go to the hospital to choose the appropriate treatment, such as shock wave lithotripsy or lithotripsy. Difficulty in urination should not take medication privately, should go to the hospital, follow the doctor’s instructions for treatment, the drug should be applied under the guidance of the doctor.