Osteoarthritis of the knee is a chronic osteoarthritic disorder caused by degeneration and osteophytes of the knee cartilage, also known as proliferative arthritis of the knee, degenerative arthritis and osteoarthrosis. The disease occurs mostly in middle-aged and elderly people, but also in young people; it can develop unilaterally or bilaterally. The clinical manifestations of osteoarthritis of the knee 1, the onset is slow, mostly in middle-aged and elderly obese women, often with a history of exertion. 2. The pain is aggravated by knee joint activity, characterized by paroxysmal pain at first, then persistent pain, more so at night with exertion, and obvious pain going up and down stairs. 3. The knee joint movement is limited, or even limping. Very few patients may develop interlocking phenomenon or knee joint effusion. 4. There may be popping and grinding sounds when the joint moves, and some patients have swollen joints, and joint deformity can be seen over time. 5. Knee pain is a common complaint of patients with this disease. The early symptoms are pain when going up and down stairs, especially when going downstairs, unilaterally or bilaterally, and joint enlargement, mostly due to bony hypertrophy, or joint effusion. Synovial hypertrophy is rare. In severe cases, the knee is deformed. Diagnosis of osteoarthritis of the knee 1. History of repeated strain or trauma. 2. Knee pain and stiffness, more pronounced in the morning when waking up, relieved by activity, aggravated by more activity, and relieved by rest. 3. Late pain persists, joint activity is significantly limited, quadriceps muscle atrophy, joint effusion, and even deformity and intra-articular free bodies appear. 4. Friction sounds can be detected during knee flexion and extension activities. 5. Frontal and lateral X-rays of the knee joint show lip-like osteophytes on the joint edges of the patella, femoral condyles, and tibial plateau, sharp tibial intercondylar ridge, narrowed joint space, dense subchondral bone, and sometimes intra-articular free bodies. The treatment of osteoarthritis of the knee joint conventional treatment: 1, non-surgical treatment (conservative treatment) including physical therapy, drugs, injection therapy and Chinese herbal medicine treatment. 2. Surgical treatment (1) Knee arthroscopic exploration and cleaning This is a new and safe technique for the diagnosis and treatment of knee diseases, which makes the patient suffer less pain and complications, and has the characteristics of fast recovery and significant curative effect. (2) Knee joint replacement Artificial knee joint replacement is the surgical replacement of the diseased knee joint partially or completely by artificially manufactured joint parts.