It is possible to have advanced pancreatic cancer without pain. Some pancreatic cancer patients have tumors on the pancreas that do not invade the pancreatic peritoneum or do not invade the plexus in the abdominal cavity, which will not cause pain. But there is also a possibility that the tumor may metastasize to the liver or the lungs, which also belongs to the advanced stage. Even at the most advanced stage of life with pancreatic cancer, the tumor on the pancreas is still relatively small. It is not the tumor on the pancreas that causes the patient’s death, but the tumor that has metastasized to the liver or other distant metastatic sites that causes the patient’s death. It is possible for a patient with advanced pancreatic cancer to have no pain from the beginning to the end of the disease. Pain is only a symptom that a patient with pancreatic cancer may experience, but not all patients will experience pain.