There are more treatment options for colon cancer liver metastases, including surgery, chemotherapy and targeted therapy, translational chemotherapy, palliative therapy, etc., as follows: 1. Surgery: If the liver metastases can be surgically removed in one stage, surgery can be done, that is, laparoscopic surgery to remove the patient’s colon cancer and lymph node dissection is required. For metastases in the liver, they can be removed or excised in one stage. If it cannot be resected in one stage, it can also be resected in the second stage; 2. chemotherapy and targeted therapy: after surgery, chemotherapy and targeted therapy are needed; 3. conversion therapy: if the patient has more liver metastases and cannot be resected in one stage, the patient can be suggested to do conversion therapy first, and wait for a period of time to review and understand the changes of the patient’s colon tumor and liver metastases. Then consider whether to do surgery for treatment. 4. Palliative treatment: Applicable to those with extensive metastases that cannot be operated.