Strabismus in newborns may be related to trauma, or it may be caused by abnormal development of extraocular muscles or craniocerebral lesions. 1. Trauma: The loss of extraocular muscles during birth due to difficult labor or forceps assisted delivery may cause strabismus, resulting in eye movement disorders, which may lead to squinting of the newborn’s eyes. 2. Abnormal development of extraocular muscles: Some newborns have abnormal development of extraocular muscles, such as abnormal length of extraocular muscles or deviation of attachment point of extraocular muscles, etc., which may cause strabismus, resulting in newborns’ eyes being tilted. 3. Craniocerebral lesions: for example, hypoplasia of the corpus callosum, atlanto-occipital malformation, depression of the base of the skull, etc., all of which may lead to abnormalities in the nerves innervating the extraocular muscles, resulting in impaired eye movements, which may cause the eyes of newborn babies to be tilted. Newborns with slanted eyes may also be caused by other reasons, partly physiological factors, if the symptoms are serious, should seek medical treatment as soon as possible, after clarifying the causes, to give targeted treatment.