Children infected with Helicobacter pylori often need to take medication based on the presence of eradication indications. 1. Indications for eradication: H. pylori testing is recommended for children with peptic ulcers, children undergoing endoscopy for dyspepsia, children with unexplained iron-deficiency anemia, children searching for the cause of idiopathic thrombocytopenic purpura, and children with first-degree family members who have stomach cancer. 2. Screening method: Carbon 13 breath test is recommended for the detection of H. pylori. 3. Medication: The treatment of H. pylori infection in children is proton pump inhibitor and two antibiotics, the proton pump inhibitor is recommended to be omeprazole, and the antibiotics are recommended to be amoxicillin clarithromycin and metronidazole. All related medications should be used in accordance with medical advice. It is recommended that children infected with Helicobacter pylori should go to a regular hospital in a timely manner, to be evaluated by a professional physician to choose the most appropriate treatment plan, in order to obtain the best prognosis.