Facing the sea, spring is in full bloom. The spring is here, many young couples in the work of the busy start to plan to start the “baby” project, but unfortunately, the following disease of young couples, this time to get pregnant is appropriate? In fact, it has nothing to do with the season, whether you can get pregnant or not depends not on the temperament, but on the condition. I. Tuberculosis Tuberculosis is a complex group of Mycobacterium tuberculosis, causing chronic lung infectious disease. The main clinical manifestations are low fever in the afternoon, night sweats, fatigue, weakness, night sweats. In women, a slight increase in body temperature is seen before menstruation and does not return to normal after menstruation. Other systemic symptoms include loss of appetite, weight loss, irregular menstruation in women, irritability, palpitations, and peachy cheeks. The incidence of pregnancy complications such as gestational toxicity, vaginal bleeding and obstructed labor are significantly increased due to TB, and the rate of miscarriage is reported to be 9 times higher in pregnant women with TB. Therefore, women of childbearing age with tuberculosis should pay great attention to whether they are pregnant or not. 1, timing of pregnancy The symptoms of tuberculosis require a long period of drug treatment, so after the occurrence of symptoms of tuberculosis, the patient is suitable for pregnancy and childbirth, so that it is easy to make the treatment of tuberculosis drugs have a great impact on the fetus. The symptoms of tuberculosis usually require a six-month period after complete cure and discontinuation of medication before pregnancy can begin. The effect on the fetus will not be so strong, and the pregnant woman can safely carry out pregnancy and childbirth, and the baby will be healthy. 2. Indications for maintaining pregnancy 1) Recovery stage of mild tuberculosis; mild pregnancy reactions; patients who have not used many drugs in the past and have effective drug chemotherapy. 2) Pregnancy can be maintained under close monitoring with obstetricians and tuberculosis physicians and strong chemotherapy in the case of older primigravida who have not yet had children. 3) Pregnant women with no serious heart, liver or lung complications and who can tolerate pregnancy, spontaneous delivery and cesarean section. 4) Simple pulmonary tuberculosis, no severe or combined extra-pulmonary tuberculosis that requires long-term treatment, such as: tuberculous meningitis, tuberculous pericarditis, abdominal or pelvic tuberculosis, lymphatic tuberculosis, bone tuberculosis, renal tuberculosis. 3. Indications for termination of pregnancy 1) Severe active tuberculosis, including multidrug-resistant tuberculosis; tuberculosis combined with the above-mentioned extrapulmonary tuberculosis requiring long-term treatment; tuberculosis combined with recurrent hemoptysis. 2)Those with severe pregnancy reaction and ineffective treatment; those with tuberculosis with hypertension, cardiac, hepatic and renal insufficiency, and those who cannot tolerate pregnancy, natural delivery and cesarean section. 3) HIV infection or AIDS pregnancy complicated by tuberculosis; diabetic pregnancy combined with tuberculosis; tuberculosis with other systemic chronic diseases. 4) Once the decision is made to terminate the pregnancy, it should be done within the first 3 months of pregnancy, because it is quite difficult to terminate the pregnancy in the second trimester, often only through cesarean section or artificial induction of labor to terminate the pregnancy, which will greatly increase the chances of bleeding and infection, and the mortality rate is significantly higher. Second, hepatitis B Can I get pregnant with hepatitis B? In fact, this contains three layers of meaning, one is whether a couple with hepatitis B can conceive a child. The second is whether the baby will also be hepatitis B. The third is whether it will be transmitted to each other. After the hepatitis B virus invades the liver cells, the hepatitis B virus itself does not directly cause liver cell lesions, but the surface antigen, e antigen and core antigen of the virus replication are released on the liver cell membranes, stimulating the body’s immune system to cause damage to the liver cells. Hepatitis B virus is usually stored in the patient’s blood, breast milk, semen, vaginal fluid, saliva and other fluids, so hepatitis B is generally transmitted through body fluids. 1.Can I have a baby? The main effects of male hepatitis B patients on fertility and sex life are: some patients with chronic hepatitis can cause impotence and hypogonadism or spermatorrhea, which may lead to poor sperm motility, before pregnancy, routine sperm examination can be performed. For patients with chronic hepatitis B, they can control the primary disease, exercise moderately, enhance their immunity and physical fitness, and avoid using sexual function enhancing drugs such as sildenafil tablets to avoid aggravating the burden on the liver and worsening the condition. Male hepatitis B patients should abstain from sexual life. In most cases, hepatitis B patients can conceive a baby. 2. Will the baby get hepatitis B? The hepatitis B virus can be transmitted from mother to child, but it is important to grasp the timing of pregnancy to see if your baby will get hepatitis B. Patients with hepatitis B can have a healthy baby under the supervision of our doctors by choosing a good time. If the hepatitis B virus DNA has been negative, the five indicators of hepatitis B suggest that a person with “small three positives” can get pregnant at any time. If the hepatitis B virus DNA is positive and the liver function is normal, the patient can get pregnant, but needs to do a good job of blocking mother-to-child transmission, especially for patients with high viral load, to prevent hepatitis activity during pregnancy and to block mother-to-child transmission by immunization immediately after the birth of the newborn. If the hepatitis B virus DNA is positive and the liver function is not normal, the patient needs to be treated so that the liver function can be restored to normal and can remain normal for a period of time after stopping the medication, and pregnancy can be considered at this time. If a hepatitis B patient is pregnant accidentally, he needs to do liver function and hepatitis B virus DNA tests. If he only carries the virus and has normal liver function, he can continue to be pregnant under the test of a specialist, and patients with high viral load can consider antiviral treatment in the later stages of pregnancy. If in the acute active phase of hepatitis, pregnancy should be terminated. Patients with hepatitis B virus infection should not conceive in the following six cases: acute hepatitis B with significant liver function abnormalities; active chronic hepatitis B with abnormal liver function prone to heavy hepatitis; hepatitis B cirrhosis; chronic hepatitis B with severe extrahepatic system manifestations, such as nephropathy and remittance; abnormal liver function with significant symptoms that make the pregnant woman unable to tolerate and terminate the pregnancy; hepatitis B virus infection with gynecological diseases that make pregnancy inappropriate. The hepatitis B virus can be transmitted from father to child. Hepatitis B virus can be transmitted from father to child, male HBV can enter the testicular tissue and semen through the blood-testis barrier, HBV-DNA present in the male reproductive system can be integrated into the sperm, and normally complete the fertilization process into the egg cell, replication and expression during embryonic development, the fetus is bound to form HBV virus particles, so that the fetus is born as a carrier, in fact, the probability of father-to-child transmission of hepatitis B is very small. In fact, the probability of father-to-child transmission of hepatitis B is very small, and the timing of pregnancy refers to the former. 3. Is it transmitted to each other? First of all, hepatitis B virus can be transmitted through blood, breast milk, semen, vaginal fluid, saliva, etc. Intimate contact between husband and wife can transmit the virus to each other, but if you do the following measures, the chances of transmission are very small. 1) When preparing for pregnancy, those who are positive for hepatitis B surface antigen should have a comprehensive check of liver function, hepatitis B virus level, e antigen, e antibody and core antibody to know whether they are infectious and the intensity of infection. 2)The other party should do a good examination of hepatitis B virus markers and liver function. If the other party is negative for hepatitis B virus surface antibody, it means that he/she lacks specific immunity to hepatitis B virus and should be vaccinated against hepatitis B as early as possible.