Blisters on the buttocks can be considered in the following cases: first, genital herpes, which can appear in clusters on the perineum, labia, penis, and scrotum in addition to the buttocks. The performance of blisters, papules, papules, etc., is due to allergic reactions caused by wearing metal jewelry or wearing non-cotton material underwear, clinical treatment can be applied to levocetirizine hydrochloride tablets orally and topical dinaide cream mixed with butalbital hydroxy acid cream for treatment.