Diabetic foot – Wagner classification 1, 2: The use of nibble clearing and dressing changes can prevent further aggravation of the diabetic foot. In severe diabetic foot – Wagner classification 4-5, treatment of the trauma bed is a multi-step process: firstly, the trauma should be fully exposed. Acute septic infection should be promptly incised and drained; however, most diabetic foot infections have no fluctuating sensation due to severe vascular lesions. Once it is clear that there is infection or dead bone in the deep tissue below the subcutaneous tissue of the foot, the skin is cut to fully expose the trauma. The trauma surface is divided into black, yellow, red and pink phases, which represent the tissue necrosis, inflammatory exudation, granulation tissue and epithelialization phases of the trauma healing process, respectively. The black phase and yellow phase mainly use nibbling clearing and changing therapy to remove or scrape away the necrotic load, bacterial load, and pathological load bit by bit without damaging normal tissues. In the process of repeatedly and repeatedly clearing the wound, the moist and humid environment of the wound surface is always maintained to promote the growth of granulation tissue and accelerate the epithelialization of the wound surface. Different drugs are applied topically according to the different periods and wounds of the diseased foot.