Bile reflux gastritis is generally not serious and can be cured with active treatment. Bile reflux gastritis is mainly caused by the reflux of bile from the duodenum to the stomach, which leads to damage to the gastric mucosa, and it is easy to be infected with Helicobacter pylori bacteria, which leads to frequent epigastric pain, abdominal distension, nausea, vomiting and other symptoms, and it may even lead to vomiting of blood and black stools. If the condition of bile reflux gastritis is mild and there is no H. pylori infection, it is usually necessary to take gastric mucous membrane protector and gastric motivation drugs, such as magnesium alumina carbonate, aluminum thiogluconate, mosapride, domperidone, and can also be combined with drugs to inhibit gastric acid secretion, such as rabeprazole, omeprazole. If Helicobacter pylori infection is clearly present, a quadruple regimen of one proton pump inhibitor, one bismuth agent, and two antibiotic drugs, e.g., omeprazole, bismuth potassium citrate, azithromycin, amoxicillin, etc., is required. The condition of bile reflux gastritis is very easy to repeat, must actively cooperate with the doctor medication, and the above drugs should be used under the guidance of a doctor.