The typical symptom of gastric ulcer is epigastric pain, which can be dull, burning, distending, severe, and hunger-like discomfort in nature. Characteristics of gastric ulcer pain: 1. chronic process, which can last for several years or more than 10 years; 2. recurrent or periodic attacks, which can last for weeks or months, with seasonal attacks, typically occurring at seasonal changes, such as the onset of fall and winter and winter-spring; 3. some patients have rhythmic epigastric pain associated with meals, mostly postprandial; 4. abdominal pain can be relieved by acid-suppressing or antacid agents. Some cases only show indigestion symptoms such as epigastric distension, epigastric discomfort, anorexia, belching, and acid reflux. There is another category of asymptomatic ulcers, which can be seen at any age, and are more common in patients taking long-term NSAIDs and in the elderly. Treatment of peptic ulcers includes medication, patient education, endoscopic treatment and surgery. The main drugs used to treat gastric ulcer are: 1. Drugs that inhibit gastric acid secretion include: H2 receptor antagonists such as famotidine, ranitidine, etc., and proton pump inhibitors (PPI) such as omeprazole, lansoprazole, etc. 2, eradication of H. pylori: the current program for the eradication of H. pylori is a quadruple therapy, that is, 1 PPI + 2 antibiotics + 1 bismuth, a course of 10-14 days. The commonly used antibiotics are clarithromycin, amoxicillin, metronidazole, etc. 3. Gastric mucosal protective agents: bismuth (such as bismuth potassium citrate, etc.), weak alkaline antacids (magnesium aluminum carbonate, aluminum phosphate, aluminum hydroxide gel, etc.). Patient education is also an important part of gastric ulcer treatment. Patients should take proper rest and reduce mental stress; improve eating patterns, quit smoking, alcohol and drinking less strong tea and coffee, and stop using unnecessary non-steroidal anti-inflammatory drugs, etc. Endoscopic treatment is mainly used for patients with bleeding peptic ulcer, combined with pyloric distortion or stenosis causing obstruction. With the wide application of PPI and the continuous development of endoscopic treatment technology, the treatment of most gastric ulcers and their complications no longer requires surgical intervention. However, surgical treatment should be considered in the following cases: ① when complicated peptic hemorrhage is not treated by drugs, gastroscopy and vascular intervention; ② when acute perforation or chronic penetrating ulcer is not effective; ③ when scarring pyloric obstruction is not effective by endoscopic treatment; ④ when gastric ulcer has cancerous changes. In conclusion, gastric ulcer is a common disease, but there are more mature treatment methods. Once the above symptoms are found, all ulcers should be suspected and should be examined promptly, and different treatments should be chosen according to the patient’s own condition.