Many drugs can have an adverse effect on the quantity and quality of sperm in male semen, resulting in men not easily conceiving women or having abnormal embryo quality after pregnancy. The drugs for the treatment of tuberculosis also have significant reproductive toxicity, affecting the number and vitality of sperm, and should be suspended during the preparation for pregnancy; 3. Sex hormone drugs, when men take sex hormone drugs, have a significant impact on reproductive function and should be avoided. Strictly speaking, it is better to avoid taking all drugs during the preparation for pregnancy.