Uremic patients die due to complications of heart disease or brain disease, which are analyzed below: Uremia is the end stage of chronic renal failure, which can damage the heart, brain and other organs due to excessive toxins in the body, and can cause increased blood pressure and accelerated atherosclerosis. Therefore, patients with uremia often die because of cardiac reasons, such as heart failure, arrhythmia, and sudden cardiac death. The symptoms in this case are chest tightness, breathlessness, arrhythmia, sudden respiratory and cardiac arrest, etc. Death may also be due to brain disease, such as brain hemorrhage and massive cerebral infarction. The symptoms include confusion, incontinence, nausea, vomiting, tonicity of the limbs, and unequal pupils on both sides.