The patient has a headache feeling at night, the cause of this situation.1. Consider caused by neuropathic pain, vascular headache.2. The possibility of headache due to the drop of temperature at night or the patient suffers from other stimuli during sleep is also very high.3. The presence of occupational disease in the brain, or the patient’s presence of schizophrenia and so on, may also lead to headache. If the patient is middle-aged or old, he/she should carry out CT examination of the brain in time, and if necessary, carry out MRI and EEG examination. Because cerebral ischemia caused by cerebral atherosclerosis should also be considered, imaging of the cerebral arteries should also be performed when necessary to determine whether there are plaques on the walls of the lower arteries, narrowing of the lumen of the blood vessels, etc., and based on the results of the examination, the best treatment should be formulated.