Mycoplasma is a conditionally pathogenic pathogen that is present in the vagina of normal individuals and requires no treatment if asymptomatic, with no adverse effects on the fetus. If Mycoplasma causes infection, it may have some effect on the fetus, such as intrauterine infection, leading to miscarriage, preterm labor, or the emergence of neonatal respiratory distress syndrome and other diseases. Pregnant women with mycoplasma infections are prone to intrauterine infections, which can cause miscarriage or preterm labor, or can lead to fetal growth retardation during pregnancy. A more serious infection in the uterine cavity will result in cloudy amniotic fluid, causing intrauterine ischemia and hypoxia, fetal respiratory distress, or even intrauterine distress, leading to fetal death. If mycoplasma infection is detected during pregnancy, it should be treated as soon as possible to control the symptoms under the guidance of a doctor. If Mycoplasma infection is detected before pregnancy, it should be treated aggressively and the symptoms should be completely controlled before pregnancy.