A, neurogenic bladder can be completely cured neurogenic bladder is caused by damage to the innervated bladder nerves, more can not be completely cured. And neurogenic bladder can be aggravated with time, recurrent urinary tract infections, urinary incontinence and with progressive reflux upper urinary tract damage and impaired renal function, not only seriously affect the quality of life of patients, but also may lead to the emergence of uremic syndrome, threatening life. Therefore, although neurogenic bladder cannot be completely cured, it can be treated to achieve a “balanced bladder” (i.e., as close as possible to a normal bladder in function) according to its urodynamic type, in order to reduce the pressure in the bladder, protect the kidney function, and improve urinary symptoms and quality of life. Second, self-cleaning intermittent catheterization (CISC) indications CISC is the most important discovery in the treatment of neurogenic bladder in the past three decades, and it has strict indications. It is mainly indicated for patients with urodynamically confirmed bladder dysfunction progressing to non-contraction of the detrusor muscle for various reasons, while some bladder capacity and good compliance exist. The aim of its CISC is to replace the function of voluntary bladder emptying, thus preserving the morphological and functional safety of the kidney and allowing the patient to return to society. Third, the method of self-cleaning intermittent catheterization (CISC) Clinicians briefly explain to patients about normal lower urinary tract anatomy and teach them to perform CISC properly. specific methods: (1), first patients wash their hands with soap and use a 12-14Fr single-lumen catheter, full length 400mm. 125px before applying lubricant to lubricate the catheter to reduce insertion pain. (2), male patients take standing or sitting position, apply wet towel or wet wipes to scrub the external urethral opening, hold the catheter in the right hand, fix the penis with the left hand to insert the urethral opening with gentle movements. After draining the urine from the bladder, gently remove the catheter, record the volume and color of urine, and rinse the catheter with water and store it properly. (3) For female patients, sit mostly in a bent knee position, place a small mirror in front of the perineum, apply a wet towel or wet wipe to scrub the perineal area or the external urethral opening, hold the catheter in the right hand, separate the labia with the left hand and look at the mirror to insert the catheter into the urethra. The rest is the same as for male patients. (4) The patient should adjust the water intake during CISC to maintain a certain rate of urine production during the day to help prevent infection. Catheterization is required once a day at night before going to bed and early in the morning after waking up. The time interval of catheterization during the day depends on the functional state of the bladder and generally requires that the volume of urine drained each time is not more than 400 ml and less than the relative safe volume. (5).The catheter can be used repeatedly, if the smooth material is broken or used for more than 1 week, it should be replaced in time. (6).Urinary routine and urine culture should be rechecked every 3 months during CISC, and urological ultrasound should be rechecked every 3-6 months to understand the condition of upper urinary tract. (7), for the discovery of febrile urinary tract infection (defined as positive urine bacterial culture with temperature ≥ 38 ℃) and urethral injury such as sarcoid hematuria should be given timely treatment.