Flesh bumps on the foreskin may be the result of diseases such as pearly penile papules, condyloma acuminatum and syphilis. 1. pearly penile papules: the etiology of this disease is unknown, studies have shown that it may be related to physiological developmental variations, circumcision, poor personal hygiene, circumcision coronal groove infection and other factors. The main symptom is that the coronal edge of the penis and the coronal groove will appear pearly translucent pimples, which can be manifested as flesh bumps on the foreskin. 2. acromegaly: this disease is caused by human papilloma virus infection, the common way of transmission is sexual intercourse, the main risk factors are unsafe sex, multiple sexual partners. The majority of patients are asymptomatic, with the development of the disease, the male patients of the glans, the coronary groove and other places will appear light red, soft, cauliflower-shaped, papillary pimples. 3. Syphilis: the disease is caused by syphilis spirochete infection, can be transmitted through sexual contact, mother and child, blood and other ways. Usually male patients will appear round red spots on the penis, glans and other places, with the development of the disease, there will be papules, maculopapular rash, pustules and other lesions, so the patient’s foreskin long flesh bumps may be syphilis. When the male foreskin long flesh bumps, should promptly go to the hospital to clarify the specific causes, so as not to delay the condition.