Liquefactive necrosis is a term used in medical pathology. Specifically, it refers to the fact that due to the less coagulable proteins in the necrotic tissue or the release of a large number of hydrolytic enzymes by the necrotic cells themselves and infiltrating neutrophils, or the fact that the tissue is rich in a large amount of water and phospholipids, when the cellular tissue is necrotic it is highly susceptible to dissolution and liquefaction, which is referred to as liquefactive necrosis. Due to the structural characteristics of the brain and pancreas, these two are more prone to liquefactive necrosis. Other organs such as the heart, kidney, liver, small intestine, etc. are less prone to it.