Bone marrow edema after ankle sprain needs anti-infection treatment, infrared irradiation and topical compresses to reduce swelling to recover gradually. 1. Anti-infection treatment: bone marrow edema is likely to be caused by inflammation of the bone marrow tissue, there may be bacterial infection, if necessary, you can follow the doctor’s instructions to take amoxicillin or levofloxacin and other antibiotics to actively treat. 2. Infrared irradiation: infrared irradiation on the part of bone marrow edema can promote the dissipation of local tissue bruising and edema, which can help the recovery of bone marrow damaged tissues. 3. External oedema: If the local edema is relatively serious, you can also use magnesium sulfate and other strong permeability of the drug to the local external application, can promptly reduce swelling and pain, reduce the pain of patients. In the ankle sprain may occur after bone marrow edema, this time must be appropriate rest and actively observe the changes in the affected area, if the edema continues to aggravate, the need for timely medical examination. The use of drugs should be in accordance with medical advice.