Kidney failure refers to renal failure. Kidney failure stage IV may affect patients’ digestive system, respiratory system, cardiovascular system and so on, and symptoms such as loss of appetite, respiratory difficulty, arrhythmia and so on may occur. 1. Digestive system: Kidney failure stage IV affects the patient’s digestive system and may cause symptoms such as loss of appetite, nausea, vomiting, abdominal pain, diarrhea and so on. 2. Respiratory system: Kidney failure stage IV affects patients’ respiratory system and may cause symptoms such as dyspnea, shortness of breath, chest tightness and shortness of breath. 3. Cardiovascular system: renal failure stage IV affects patients’ cardiovascular system and may cause arrhythmia, elevated blood pressure, uremic pericarditis and other symptoms. Renal failure stage IV also affects the patient’s hematopoietic system, nerve function, resulting in bleeding gums, black stool, depression, dizziness, headache and other symptoms, the above symptoms should be timely to listen to the doctor’s advice to improve the examination to clarify the diagnosis, targeted treatment.