Blood creatinine reaches 800umol/L, first distinguish whether it is acute renal failure or chronic renal failure uremic syndrome, because the blood creatinine is high, can need to carry out renal replacement therapy, including hemodialysis, peritoneal dialysis, if it is chronic people can also choose kidney transplantation. If it is acute renal failure some patients are treated for the cause and it is possible to get rid of dialysis treatment. Patients with chronic renal failure should choose dialysis according to their own condition and according to the doctor’s guidance. Hemodialysis needs to be done three times a week, come to the hospital and go through the dialyzer. Peritoneal dialysis is performed at home and exchanged four times a day, relying on one’s own peritoneum as a semi-permeable membrane for the purpose of toxin removal. Both hemodialysis and peritoneal dialysis, each have certain complications. Hemodialysis is prone to hypotension, hypertension, and imbalance syndrome, while peritoneal dialysis is prone to catheter-associated infections and peritonitis, which need to be properly treated and managed.