Skin acne is generally referred to as acne, the etiology of which is more complex and is related to high androgen levels, abnormal keratinization of follicular sebaceous gland ducts, and inflammatory reactions.
1. High androgen levels: The target unit of acne is the sebaceous gland of the hair follicle, and the development and secretion of the sebaceous gland is directly controlled by the endocrine system. High androgen levels in the body can cause sebaceous gland development and increased sebum overflow, which is the basis for acne.
2. Abnormal keratinization of follicular sebaceous gland ducts: The excessive proliferation of keratinocytes in acne patients causes the thickening of the epithelial cell layer of the sebaceous gland ducts, which results in the acute occlusion of the follicular sebaceous gland ducts, and the formation of acne due to follicular bulging.
3. Inflammatory reaction: microorganisms such as Propionibacterium acnes grow and multiply in large quantities in the hair follicles and on the surface of the skin, as well as a variety of inflammatory stimulus factors that constantly appear during the development of acne, which can lead to aggravation and fluctuation of acne.
It is recommended that patients with recurring acne go to a regular hospital, follow the doctor’s instructions for treatment, and do not blindly use medication on their own.