Acute gastroenteritis is a common disease, for which the main treatment is to address the causes and improve the symptoms. Acute gastroenteritis is mainly caused by bacterial inflammatory infections, often resulting from the consumption of unclean food. Because of frequent nausea, vomiting, diarrhea, as well as abdominal pain and even fever, it is necessary to seek medical attention in a timely manner and consider drip antibiotics, as well as replenish electrolytes, correct the imbalance of acid-base balance and release the very smooth machine spasm. Aminoglycoside antibiotics, cephalosporin antibiotics and quinolone antibiotics (age less than 18 years, quinolone antibiotics are prohibited) can be chosen, depending on the specific condition, and if severe, a combination of drugs can be used. If abdominal pain and diarrhea are severe, scopolamine injection can be used, which can release smooth muscle spasm and inhibit glandular secretion, which can improve the symptoms of abdominal pain and diarrhea. Montelukast can also be added to stop diarrhea. If the fever systemic poisoning symptoms are heavy, adrenal glucocorticoids can be given, the most commonly used drug is dexamethasone, which can effectively relieve the systemic poisoning symptoms and smoothly pass the acute phase of the disease, and vitamin C can also be given to help enhance the body’s immune function. In addition, proprietary Chinese medicines such as Huo Xiang Zheng Qi Capsules, Feng Polygon Gastrointestinal Kang, and Ge Gen Scutellaria Pills are also good for the treatment of acute gastroenteritis. In conclusion, for acute gastroenteritis, medication is the main treatment, supplemented by enhanced care and improved diet.