When the condition of patients with acute gastroenteritis is serious, it can be treated by infusion, which mainly includes replenishment of water and electrolytes, anti-inflammatory and gastric mucous membrane protection drugs.1, replenishment of water and electrolytes: if the patient vomits a lot of gastric contents with severe vomiting, or if the patient passes a lot of dilute and watery stools with severe diarrhea, and the patient suffers from symptoms of dehydration and electrolyte disorders, such as thirst, low urine output, fatigue and palpitation, the patient may be treated with intravenous infusion of saline, glycol saline and potassium chloride under the guidance of the doctor. Saline, sugar saline and potassium chloride can be infused intravenously under doctor’s instruction to replenish water and electrolytes; 2. Anti-inflammation: If the percentage of white blood cells and neutrophils is increased, or a large number of white blood cells can be seen in stools, and there is clear evidence of bacterial infection, intravenous infusion of antibiotics targeting gram-negative bacilli such as ciprofloxacin, levofloxacin, etc. can be given as prescribed by the doctor to carry out anti-inflammatory treatment; 3. Protecting the gastric mucous membrane: Follow the doctor’s instructions for intravenous input of proton pump inhibitors to protect the gastric mucosa and relieve discomfort. Patients should pay attention to diet, it is advisable to eat a light, easy to digest diet, such as millet porridge, noodles, etc., avoid eating cold, spicy and irritating food, so as not to aggravate the condition.