Getting up in the morning with swollen hands may have the following reasons: 1. It is possible that the hands get cold when sleeping at night, resulting in local vasospasm, poor blood circulation and ischemic swelling. In addition, it is also possible that when sleeping, due to the limb or the person next to the hand pressure for a longer period of time, can also cause ischemia and lead to swelling. Usually after getting up in the morning to move around, promote local blood circulation, the symptoms can be relieved immediately. 2, there may be neurosensory symptoms, commonly carpal tunnel syndrome or cervical spondylosis, compression of the nerve roots of the upper limbs, nerve sensory impairment. In this case, it is usually manifested in the palm of the hand feeling more swollen, numbness, in fact, there is no local skin or soft tissue edema formation. 3, it may be the allergic manifestation of the skin, it may be sleeping in the bed with mites, or contact with allergic substances, which leads to the swelling of the hand. Usually, this condition is accompanied by symptoms of itchy skin.