Side effects such as allergic reactions, systemic reactions, and localized reactions may occur with vaccination. These vary from person to person, and some patients have no obvious discomfort after vaccination. The most common allergic reaction to vaccination is allergic reaction, which can be manifested as rash, macular rash, papule, rubella, and can be manifested as itchy skin, and if severe allergic reaction can be manifested as dyspnea, palpitation, chest tightness, and so on. Some systemic reactions can occur with vaccination, such as dizziness, chest tightness, chest pain, diarrhea, abdominal pain, headache, muscle aches, joint pain. After many vaccinations, there is a possibility of local reactions, such as localized hardness, redness, swelling, itching, pain, and ulceration. Because of the possibility of more side effects, it is important to observe the vaccination site for half an hour before leaving, and if a severe allergic reaction occurs, you should go to the hospital as soon as possible.