Newborns with biliary obstruction may have clay-like stools, which are pale and whitish in color. The time of onset varies depending on the severity of the biliary obstruction and is usually around 1 to 3 weeks after birth. Congenital biliary atresia causes the bilirubin in the baby’s bile to be unable to enter the intestines, and the stools are white and clay-like due to the lack of pigment production. Usually, children with complete biliary obstruction have white stools about 1 week after birth. In patients with slow progressing biliary obstruction, the white stools may not appear until 3 weeks after birth. Neonatal biliary obstruction is usually caused by heredity, viral infection, etc. Parents need to take their children to the hospital for a thorough examination because of the seriousness of the disease. If the extrahepatic bile duct is open and the gallbladder is of normal size, a Roux-en-Y anastomosis can be performed between the gallbladder or extrahepatic bile duct and the jejunum. If the extrahepatic bile ducts are completely atretic, liver transplantation is needed. Enhance the nursing care in daily life and feed reasonably. It is recommended that newborns with symptoms of biliary obstruction should go to the hospital in time, and under the guidance of the doctor to actively treat the disease, to avoid delaying the condition.