The causes of high platelets can be categorized into reactive and clonal increase, and the treatment can be categorized into etiologic treatment and drug treatment.
1. Reactive thrombocytosis can be seen in acute infection, acute hemolysis, some cancer patients, because reactive thrombocytosis has self-limiting, low risk of thrombosis. Therefore, only the primary pathology needs to be treated, without routine antiplatelet therapy.
Such as anti-infection (levofloxacin), anti-hemolysis (dexamethasone), radiotherapy (carboplatin), immunotherapy or targeted therapy (gefitinib) cancer patients.
2. Clonal thrombocythemia (common causes include primary thrombocythemia, chronic granulocytic anemia, true erythrocytosis, and primary myelofibrosis), which is prone to thrombosis and is a common complication leading to death in this group of patients.
Therefore, the key to treatment is to minimize thrombosis with antiplatelet (aspirin, clopidogrel, etc.) therapy and single platelet transfusion. In addition, treatment of the primary disease, such as oral imatinib for chronic granulocytic leukemia, is still needed.
If you have high platelets, you should consult a doctor for diagnosis and treatment.