The main difference between Bacillus quadruple and Bacillus triple is that the number and type of strains are different, which is mainly used for treating indigestion, diarrhea and other discomforts caused by intestinal flora imbalance, and can regulate the intestinal flora. Bifidobacterium tetragonum contains four strains, while Bifidobacterium tricuspidum contains three strains, therefore, the number of strains of the two drugs is different. Bifidobacterium tetragonum are Bifidobacterium infantis, Lactobacillus acidophilus, Enterococcus faecalis, and Bacillus cereus. The triple bacilli are Lactobacillus acidophilus, Enterococcus faecalis, and Bifidobacterium longum, which shows that the number of strains of Bifidobacterium tetragonnosum and Bifidobacterium triticum are different. Bacillus quadraticus and Bacillus trichotomus are a kind of live bacterial preparation, the drug should be used under the guidance of a doctor, and should not be used on its own to avoid adverse reactions.