Liver hardness of 16.8 kPa is mostly related to liver fibrosis and cirrhosis, and should be treated with daily care, medication and surgery to relieve symptoms. 1. Liver fibrosis: it is a pathological phenomenon mainly produced by long-term damage to the liver, usually related to viral hepatitis and alcoholic hepatitis. Treatment should remove the cause as soon as possible, and quit drinking in time, and then carry out anti-hepatic fibrosis treatment, at present, you can take glycyrrhizic acid preparations, such as diammonium glycyrrhizinate, magnesium isoglycyrrhizinate and so on. 2. Cirrhosis: mostly developed from hepatitis B virus infection, after diagnosis, oral antiviral drugs should be strictly followed by doctor’s prescription, such as entecavir, tenofovir, etc. If the liver function is better, interferon injection is also an option. When cirrhosis reaches the end stage, liver transplantation should be taken. Once checking the phenomenon of liver cirrhosis, you need to cooperate with the doctor to conduct a comprehensive physical examination and understand the specific changes in the liver, and then according to the diagnosis results of targeted treatment.