For patients using insulin to treat diabetes, the most common adverse effect is hypoglycemia. Hypoglycemia is a very common adverse effect of insulin, which is mainly caused by the high dose of insulin. Therefore, in clinical practice, the selection of insulin regimen and the adjustment of insulin dose during the implementation of insulin regimen need to be standardized and individualized, because each patient has different sensitivity to insulin, including the fluctuation of blood sugar, so the insulin dose is different for each patient. The initial insulin dose assessment is mainly based on the patient’s weight and the magnitude of high blood sugar to make a control. The subsequent adjustment of insulin dose is mainly based on the patient’s fasting and blood sugar before and after three meals. Therefore, the ultimate goal of all insulin doses, including the selection of the program, is to prevent the occurrence of adverse events such as hypoglycemia, in addition to lowering blood glucose. Once hypoglycemia occurs, it will have a very negative impact on the patient’s cardiovascular system and can lead to coma in severe cases.