Girls with small bumps with tenderness down there can be considered to be related to folliculitis, boils or inflammation of the vestibular gland, etc., and need to pay attention to local cleanliness and take medication or surgery according to the cause of the disease. 1. Folliculitis or boils: pay attention to the cleanliness of the skin and local hygiene, and prevent trauma; in the early stage of boils without pus, topical treatment with ichthyolite ointment, iodine tincture or mupirocin ointment; when the lesions are recurring, antibiotic treatment such as cephalosporin can be used. 3. Vestibular gland inflammation: when there is acute inflammation, pay attention to keep the local clean, can do bacterial culture to determine the pathogen, the use of targeted drugs, can also use cephalosporin or quinolone combined with metronidazole anti-infective; vestibular gland abscess is recommended to incise and drain as soon as possible, to relieve the pain; asymptomatic vestibular cysts attention to the observation of the cyst is larger than the feasibility of cystostomy. Women with pain in the perineum, need to go to the hospital specialist in time, follow the doctor’s advice on the cause of the symptomatic treatment.