Uneven perfusion of both lungs, also known as insufficient ventilation and perfusion of both lungs, is common in congenital dysfunction of both lungs or bacterial or viral infections. Clinical manifestations are that the airways are obstructed to varying degrees and the function of ventilation and air exchange is reduced. 1. Congenital dysplasia of both sides of the lungs: Because of the reduction of lung surface active substances, the retraction force of alveoli is relatively reduced, which will cause further depression of small alveoli and further expansion of large alveoli, resulting in lung atrophy. 2. Bacterial and viral infections: cause diffuse inflammatory reaction in both lungs, and ischemia and hypoxia in the lung lobes, leading to symptoms such as chest tightness. In addition, some non-infectious diseases of the lungs, such as pneumoconiosis, silicosis, bronchial asthma, etc., can also cause uneven perfusion in both lungs. Uneven perfusion in both lungs can also be seen in other causes, and patients are advised to seek prompt medical attention to avoid delaying their condition.