Cranial defects are partly due to open cranial injury or firearm penetrating injury, and some patients have residual defects due to debridement decompression or diseased craniectomy. In recent years, the proportion of cranial defects caused by debridement decompression has increased because of the good results obtained in the treatment of patients with severe traumatic brain injury. After cranial defects, firstly, patients are subjected to various kinds of external pointers due to aesthetic problems, resulting in low self-esteem and depressive psychological disorders. Secondly, patients may experience dizziness and headache, memory loss, and fear of loud noises. In addition, it may cause complications such as brain bulge, brain atrophy and hydrocephalus, which will pose a major threat to patients’ life and health. Therefore, timely skull repair surgery can not only restore the patient’s health as soon as possible, but also reduce the patient’s psychological pressure to a certain extent. Cranial repair is a relatively simple and fast recovery surgery in neurosurgery. From the current technology, there is basically no risk during the surgery and the requirement of covering the defect area can be basically achieved, but the postoperative repair effect and recovery time vary depending on the implant material and repair method. At present, our team performs polyether ether ketone peek cranioplasty with new peek implant material, embedded repair method, and personalized plan (repair + plastic surgery), and the postoperative patient has good overall shaping effect. The surgery itself is a very rapid recovery, and the patient can get out of bed on the second day after surgery, and can be discharged from the hospital in five to seven days, plus the two to three days of preoperative examination, the whole recovery time is basically about half a month.