Patient: Description of condition (onset, main symptoms, hospital visited, etc.): I was previously tested positive for mycoplasma and was given azithromycin, but never went for a review. In the past month, I felt some itching, and I went to the hospital to review the situation, the cleanliness is 3 degrees, pH 6, the test results for mycoplasma vaginitis, and mycoplasma infection is positive. After the test, mycoplasma was negative. I don’t know what to do because my husband and I are both older and anxious to have a child, and this mycoplasma has been cured and is back. Please help me. Doctor: Mycoplasma positive treatment once or twice without turning negative can not be treated, it does not matter much. Mycoplasma is also present in the normal vagina. Currently, there are some patients with similar experiences to yours who are suffering from repeated treatments that have not resulted in a negative result. In fact, many patients are over-treated, both because of misconceptions about this pathogenic infection and because individual clinics and hospitals do not regulate the use of drugs due to certain financial interests. There is also often a certain amount of false positives in the tests. If the clinical treatment is still positive and the cleanliness of vaginal secretions is normal, the treatment can be stopped, because repeated use of drugs will not only cause drug resistance, but also dysbiosis leading to secondary infection. Don’t always worry about mycoplasma, cervical examinations and cytologic smears or colposcopy should be done once a year.