When the knee hyperplasia can be used to activate blood circulation and eliminate blood stasis, anti-inflammatory and pain-relieving ointment can be applied to the local area. However, topical ointment can only improve or alleviate the clinical symptoms associated with osteophytes, but can not cure osteophytes. 1. Activating blood circulation and removing blood stasis: When patients with knee hyperplasia have an acute attack, they often feel persistent pain in the knee, and even have limited activities. Clinically, Yunnan Baiyao ointment is often used to activate blood circulation and remove blood stasis evenly applied to the affected area, and gently kneaded to help absorption, which effectively promotes blood circulation and relieves the pain. 2. Anti-inflammatory and analgesic: non-steroidal anti-inflammatory and analgesic creams such as diclofenac diethylamide cream are also commonly used to alleviate the pain symptoms caused by knee enlargement. The use of related drugs should follow the doctor’s instructions. It is recommended that patients with knee enlargement consult a doctor in a timely manner to choose the most appropriate treatment plan according to the specific condition.