Patients with swelling and pain on one side of the nose mainly include the following reasons: First, patients may not pay attention to hand hygiene and often use their hands to dig their nostrils resulting in mucous membrane rupture, so it will lead to local inflammation formation in the nasal mucosa, which will lead to swelling and pain. Secondly, it is mainly considered that the patient may have the situation of fire due to the pressure of work and life, which may lead to the boil on the side of the nasal cavity, or even the formation of cyst infection, and the patient is suggested to go to the hospital for further examination. Thirdly, it is mainly considered that the patient has neoplastic formation inside the nasal cavity, such as having nasal polyps or having papilloma in the nasal cavity, or even having malignant swelling, which may lead to swelling and pain in the patient’s nose. Regardless of which of the above causes, it is best to actively examine and further treat the patient to avoid delaying the condition.