Babies do not have fever during the day and fever at night can be seen in respiratory tract infections, tuberculosis, leukemia and other conditions, in the reasonable antipyretic treatment at the same time, need to address the cause of the treatment. Fever is a common symptom of childhood, for fever but body temperature <38.5 ℃ children can use warm water on the forehead, reduce the clothing worn by physical methods to lower the temperature; for the temperature ≥ 38.5 ℃ babies need to use antipyretic drugs such as ibuprofen, acetaminophen and other antipyretic treatments under the guidance of a doctor. At the same time for the cause of the treatment is also very important for the recovery of body temperature. If the respiratory tract infection caused by bacterial infection, need to actively use antibacterial drugs such as cefaclor, cefdinir and so on for anti-infection treatment. In case of tuberculosis, isoniazid, rifampicin, pyrazinamide and other drugs should be used for treatment. In case of leukemia and other blood tumor related diseases, chemotherapy with drugs such as vincristine and Zoerythromycin, and bone marrow transplantation if necessary are required. All of the above drugs should be used under doctor's guidance, avoid self-medication. It is recommended that children with fever should seek prompt medical attention and be evaluated for treatment by a specialist.