The average survival of 80-year-old people with acute leukemia without special treatment is only about 3 months. With chemotherapy or supportive treatment, the survival period may be prolonged by 6 months to 3 years, and the factors affecting this include physical fitness, underlying disease conditions, and tolerance of chemotherapy drugs. 1.80 year olds who are physically fit, with fewer underlying diseases and better organ function may be considered for reduced dose chemotherapy. If the tolerance of chemotherapy drugs is good, the effect of chemotherapy is remarkable and the survival period can be prolonged. The drugs include cytarabine, etc. 2. If the elderly are physically weaker, have more underlying diseases, and are less tolerant to chemotherapy drugs, they are often treated with smaller doses of chemotherapy or targeted drugs such as Vinaclat. If the therapeutic effect is obvious, the survival period can also be prolonged. The 80-year-old man with acute leukemia is recommended to be hospitalized to receive standardized treatment to improve survival, but the risk of chemotherapy complications such as infection and organ failure is high, the specific use of drugs need to be under the guidance of a physician.