The normal value of blood creatinine is 53~106μmol/L for men and 44~97μmol/L for women, and elevated creatinine can be divided into physiological and pathological factors. Blood creatinine 700μmol / L is seriously high, generally consider pathological factors, such as acute and chronic renal failure, etc., according to the cause of the general treatment, drug therapy, renal replacement therapy to control the condition. 1. Acute renal failure: there are three types: pre-renal, renal and post-renal. Pre-renal such as effective circulating blood volume is insufficient, need to timely rehydration treatment; post-renal such as urinary stones, need to be treated with lithotripsy, and larger stones can be treated with surgery as prescribed by the doctor. 2. Chronic renal failure: for patients with hypertension, strict control of blood pressure is required, and oral nifedipine extended-release tablets and amlodipine can be taken as prescribed by the doctor. If renal anemia occurs, recombinant human erythropoietin should be used. Those who meet the indication of dialysis should take renal replacement therapy, such as peritoneal dialysis or hemodialysis. Blood creatinine 700μmol / L is recommended to go to the hospital in time, under the guidance of professional physicians to timely treatment, so as not to delay the condition.