Breast calcification should be treated for the primary cause, which is usually found during the examination of ultrasound and is divided into benign and malignant calcifications. For benign calcifications, they can be followed up clinically and do not require special treatment. However, for malignant calcification, surgical treatment should be considered, and like general radical breast cancer surgery, modified radical breast cancer surgery is more often taken. However, if the lump in early stage is small, breast-conserving surgery can be considered, and after lymph node biopsy, axillary lymph node dissection can be considered. Nowadays, chemotherapy is usually done routinely after surgery, which is the case of malignant calcification of the breast. The postoperative endocrine therapy depends on the results of postoperative disease examination, for example, if there is a positive ER and PR in the postoperative examination of the breast, systematic endocrine therapy should be done. Endocrine therapy is usually 5 years, and the traditional medication is triamcinolone acetonide. Nowadays, we usually use anastrozole and other medications, and we also have to take them for 5 years to achieve perfect treatment effect.