The proper way to take spironolactone is 40 to 400 mg per day for adults and 3 to 9 mg/kg per day or 90 to 270 mg/m2 for children, which can be divided into two to four doses. Spironolactone is a synthetic steroidal compound similar in structure to aldosterone, which acts on the distal tubule and collecting duct to exert a diuretic effect. The diuretic effect of spironolactone is relatively weak, and it is mainly used to treat edema, hypertension, and primary aldosteronism due to elevated aldosterone. Adults as diuretics when used as the usual dose of not more than 40mg per day, the treatment of primary aldosteronism for 20mg to 100mg per day TID, the treatment of hypertension 40 to 80mg per day, respectively, divided into 2 to 4 times; children in the first 5 days of the body weight according to the 1 to 3mg/kg or according to the surface area of the body of 30 to 90mg/m2, divided into 2 to 4 times, and then you can adjust the dose, but not more than 3mg per day, but not more than 3mg per day. Adjust the dose, but not more than 3 to 9mg/kg or 90 to 270mg/m2 per day. Spironolactone may cause side effects such as hyperkalemia, cardiac arrhythmia liver and kidney impairment, gastrointestinal reactions, and headache. Therefore, it is recommended to take the drug under the supervision of a doctor, and it is not recommended to take it by yourself. And it is not recommended for patients with severe liver and kidney function impairment, hyperkalemia and allergy to spironolactone.