Spermatogonial cell tumors may have an effect on fertility. Spermatogonial cell tumors are germ cell tumors that originate in the testes. Since spermatogonia is a tumor sensitive to antitumor treatments such as radiotherapy, even early-stage patients are treated with radiation therapy, and the long-term toxicity of radiation therapy may cause infertility in patients. Moreover, the use of some chemotherapeutic drugs may also affect the fertility of patients to a certain extent. However, after active radiotherapy and other anti-tumor treatment, the clinical cure rate of patients is also very high, and the 5-year survival rate can reach 50%~100%. Therefore, patients with spermatogonial cell tumor should actively cooperate with doctors for treatment, and at the same time, it is recommended that family members should pay attention to communicate with patients more often, so as to make them keep a positive, optimistic and cheerful mindset.