Oral and nasal suctioning is used clinically, mostly in patients who are bedridden for a long period of time, and most of such patients are accompanied by a history of cerebral infarction, cerebral hemorrhage, long-term chronic pneumonia, and intrapulmonary infections. Such patients may present with a lack of airway patency. If the patient develops upper airway ventilation restriction, it is likely that the upper airway, including the oral and nasal cavities, has become clogged with sputum, leading to the patient’s air breathing restriction. Clinically, the recommendation for this condition is to aspirate the mouth first, as the mouth is the main place of ventilation for human respiration. If the patient has difficulty breathing, the benefits of suctioning from the mouth are mainly because: 1) the patient cooperates better; 2) the amount of sputum suctioned will be larger, and suctioning will be quicker and safer. If the patient is first suctioned from the nasal cavity, not only can the patient not cooperate, but also the amount of nasal ventilation is not as large as oral ventilation, so it is still recommended to suction from the oral cavity first. In such patients, if the patient’s family members do not cooperate well or do not know how to operate, it is recommended that sputum be suctioned under the guidance of a clinical technician or clinical nurse.