Ichthyosis of the skin on the legs usually refers to ichthyosis of the skin, which is a genetically related skin disease, and its treatment is still relatively common in the clinic as follows: First, medication: you can choose to take oral Avium capsules, or topical vitamin A acid cream, and skin moisturizer for comprehensive treatment. Second, the use of moisturizers: to pay attention to repair the skin barrier, a lot of moisturizers for emollient treatment, usually after a period of time, the patient’s lesions will not be so rough, the color will not be so much pigmentation, are improved. Third, other treatment methods: this disease is related to genetics, and it is still difficult to treat, and there are different types of ichthyosis, and the difficulty and methods of treatment differ from one type to another. This disease cannot be completely cured, but through regular oral as well as topical drugs, clinical remission can be achieved to minimize the impact of the disease on the patient in all aspects and reduce the patient’s psychological pressure.