Breastfeeding mothers need to avoid infusion of Levofloxacin, and after the infusion is required due to illness, breastfeeding is required after stopping Levofloxacin for 3 days. Levofloxacin is a quinolone antimicrobial drug, mainly used for the treatment of respiratory system infections, urinary system infections, reproductive system infections, skin and soft tissue infections. It is contraindicated for those who are allergic to quinolones, for patients under 18 years of age, and for pregnant and breastfeeding women. Therefore, it is necessary to avoid the use of these drugs during breastfeeding. Usually, if for some reason the mother needs to use levofloxacin, she should stop breastfeeding. If the disease is effectively controlled, the problem of Levofloxacin remaining in the body or passing through the breast milk and affecting breastfeeding is taken into account. Usually after 3 days of infusion, levofloxacin is nearly metabolized through the metabolic function of the mother, and it is relatively safe to resume breastfeeding at this time. Before using any medication, it is necessary to know whether the medication is contraindicated for the body, and at the same time, it is necessary to take medication under the guidance of the doctor in conjunction with one’s own condition. If a mother needs treatment, she should go to a regular hospital and ask for a doctor’s advice.