The causes of lymphoma are still unclear, and clinically, it is mainly considered to be related to gene mutation, abnormality of immune system and environmental factors. 1. Genetic mutation: If there are congenital genetic mutations, it may cause cancer, for example, genetic mutations cause abnormal division and proliferation of lymphocytes, which may lead to lymphoma in the next generation. 2. Abnormalities of immune system: Lymph is a tissue of immune system, if there are diseases of immune system, the accumulation of such diseases for a long time will easily stimulate the lymphatic system, which will lead to lymphoma. 3. Environmental factors: prolonged exposure to chemical pollution or radioactive pollution will easily cause abnormal division and proliferation of lymphocytes, which will lead to lymphoma. Lymphoma is a kind of malignant tumor and the key lies in early detection and early treatment. After diagnosis of lymphoma, chemotherapy, radiotherapy, surgery and other comprehensive treatments should be adopted according to specific conditions.