The right medicine is used to cure the disease, so to make the most of its effects, you first need to understand it! Take a look at omeprazole! Omeprazole is known as proton pump inhibitor, also known as PPI, because it can irreversibly bind to H-KATPase of stomach wall cells, thus inhibiting the secretion of gastric acid, the acid suppression effect is strong and long-lasting, so it has good effect on gastric ulcer, duodenal ulcer, acid reflux caused by “heartburn”. 1, taking time omeprazole this drug belongs to the non-prescription drugs, in the pharmacy can be purchased at will, many people know it is the treatment of gastric disease, short-term use can inhibit gastric acid secretion, the effect is good. However, some people have reflux esophagitis, especially post cardia resection patients, acid reflux is obvious, almost need to take omeprazole for years and years, because the absorption and utilization of such drugs are mostly disturbed by the food in the stomach, so it is best taken in the morning or before bedtime in an empty stomach state. If necessary, it can be taken once in the morning and once before bedtime. 2.Applications and contraindications The main indications of omeprazole are: and duodenal ulcers chronic chronic ginger gastritis, reflux esophagitis, stress ulcers, Helicobacter pylori infection, etc. have satisfactory efficacy (Note: the need for a combination of drugs, can not use omeprazole alone, but omeprazole is an important component). Therefore, many old gastric patients need to use this drug year-round, however, it should be noted that omeprazole must not be abused, nor should it be taken for a long time, in the treatment of H. pylori or have preventive measures we also recommend the need to actively supplement the Shuk Pylori probiotics, inhibit the H. pylori to reduce the side effects of the drug. Long-term use of omeprazole may also occur gastrointestinal reactions, abnormal liver function, atrophic gastritis, sexual dysfunction and other adverse reactions. Therefore, although omeprazole is one of the essential drugs for many gastric diseases, it must not be taken for a long period of time and must be taken in the doses and regimens prescribed by the doctor. Omeprazole seems to be safe, but in fact there are still more side effects. Its main effect is to improve the symptoms and it is generally not recommended for long-term use. For patients with long-term acid reflux, it is best to find the cause and change the usual eating habits before considering oral omeprazole when the symptoms are obvious, or alternating with H2-blockers such as cimetidine and famotidine.