Omeprazole administration varies according to the diseases it treats, and its indications mainly include peptic ulcer, reflux esophagitis, and Dreh-Ayer syndrome. 1. In the treatment of peptic ulcer: commonly used 20mg/dose, once/day. The maximum can be increased to 40mg/day, swallowed in the morning or divided into morning and evening, the course of treatment is usually 2~8 weeks. 2. For the treatment of reflux esophagitis: 20~40mg/times, once/day. The course of treatment is usually 4~8 weeks. 3. For the treatment of Zuo-Ai syndrome: the recommended starting dose is 60mg/dose, once/day, and then the total daily dose can be adjusted within the range of 20-120mg, and should be divided into 2 doses if the daily dose exceeds 80mg. It should also be noted that this drug is prohibited in people who are allergic to it, people with severe renal insufficiency, and also prohibited from combining with nelfinavir, and there is also the possibility of headache, diarrhea and other adverse reactions during the use of the drug. Therefore, the use of omeprazole needs, must be under the guidance of the doctor according to the actual situation of the individual standardized use of drugs, do not blindly take drugs or increase or decrease the dosage, so as not to cause adverse consequences.